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This entry was posted by Darryl on March 10, Epub Jan 1. Also we are working on developing new AAV vectors capable of crossing the blood brain barrier for effective gene delivery to the brain after intravascular infusion.

Share this post with friends! The Sena-Esteves laboratory is investigating gene therapy approaches for the treatment of neurodegenerative lysosomal storage diseases such as GM1-gangliosidosis and GM2-gangliosidoses Tay-Sachs and Sandhoff diseases.

Localized thermodynamic coupling between hydrogen bonding and microenvironment polarity substantially stabilizes proteins.

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